Nigerian clubs Enugu Rangers and Remo Stars started strong in CAF Champions League qualifiers, aiming to be the first Nigerian title-holders since 2004.
Enugu narrowly defeated Zilimadjou 1-0 in Uyo, taking a lead through Frank Uwumiro.
Zilimadjou lost home advantage as Comoros lacks a compliant stadium, making both legs of the tie happen in Nigeria.
Enugu, winners of the 1977 African Cup Winners’ Cup, seek to replicate Enyimba’s back-to-back title success.
Remo Stars battled hard to defeat FAR Rabat 2-1 in Ikenne after conceding an equalizer early in the second half.
Ismaila Sodiq’s 66th-minute goal secured a vital lead for the return match on August 25 in Morocco.
Meanwhile, Egypt’s Pyramids crushed JKU of Zanzibar 6-0 as they aim for redemption after last season’s early exit.
Al Ahly, 12-time champions, will enter in the second round against Merreikh Bentiu or Gor Mahia.
Elsewhere, Orlando Pirates drew 0-0 away against Madagascar’s Disciples.
Ghana’s Samartex edged Victoria United 1-0 away in Cameroon, with Emmanuel Mamah scoring the decisive goal to put them in a strong position for the next round.
